WebChromogranin A (CGA) is a 439-amino acid protein with a molecular weight of 48 to 60 kDa, depending on glycosylation and phosphorylation status. It is a member of the granin … Chromogranin A or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory proteins. As such, it is located in secretory vesicles of neurons and endocrine cells such as islet beta cell secretory granules in the pancreas. In humans, chromogranin A … See more Examples of cells producing chromogranin A (ChgA) are chromaffin cells of the adrenal medulla, paraganglia, enterochromaffin-like cells and beta cells of the pancreas. It is present in islet beta cell secretory granules. … See more Chromogranin A is elevated in pheochromocytomas. It has been identified as autoantigen in type 1 diabetes. A peptide … See more • Hendy GN, Bevan S, Mattei MG, Mouland AJ (February 1995). "Chromogranin A". Clinical and Investigative Medicine. 18 (1): 47–65. PMID 7768066. • Iacangelo AL, Eiden LE (August 1995). "Chromogranin A: current status as a precursor for bioactive peptides and a granulogenic/sorting factor in the regulated secretory pathway" See more Chromogranin A is the precursor to several functional peptides including vasostatin-1, vasostatin-2, pancreastatin, catestatin and parastatin. These peptides negatively … See more Variants exist for pancreastatin in various populations of the world. The variant Glycine297Serine has been shown to be more potent in … See more • chromogranin A antibody stains via Google Image [1] • Overview of all the structural information available in the PDB for UniProt: P10645 (Chromogranin-A) at the See more
What Causes Elevated Chromogranin A Levels?
WebInformatii generale. Informaţii generale – Cromogranina A. Cromogranina A este o proteină cu greutatea moleculară de 49 kD alcătuită din 439 aminoacizi. Face parte din familia graninelor care se găsesc în veziculele secretorii ale celulelor neuroendocrine. Rolul acestora este de a regla activitatea secretorie a acestor celule. WebJul 24, 2024 · Chromogranin A test is also a potential marker to detect relapse or recurrence of neuroendocrine tumors. Reduction in levels of chromogranin indicates the effectiveness of the choice of treatment. … punishment for misuse of sc/st act
Chromogranin A: Is It a Useful Marker of Neuroendocrine Tumors?
WebChromogranin A 1 is a hydrophilic glycoprotein that is stored in the chromaffin granules of the neuroendocrine cells. 2 The physiologic role of CgA has not been fully elucidated, but studies suggest that it serves as a precursor to other biologically active peptides and facilitates the production of other hormones and neuropeptides. 2-4 In … WebJul 24, 2024 · Chromogranin A test is also a potential marker to detect relapse or recurrence of neuroendocrine tumors. Reduction in levels of chromogranin indicates the … WebThe chromogranins (types A, B, and C) are a group of monomeric proteins that compose the major portion of the soluble protein extract of the neurosecretory granules of … second hand quantum taxi for sale